The article is devoted to the research and development of an automated control system for the technological process of obtaining E. coli. E. coli belongs to gram-negative rod-shaped bacteria of the Enterobacteriaceae family of facultative anaerobes. It is the most famous microbe in the world and has different types of strains. Commensal E.coli are harmless and often found in nature. Currently, great attention is paid to the use of modified E.coli for the production of recombinant proteins, amino acids. The results of mathematical modeling of the automated system are presented. The simulation was performed using SimInTech and MathCAD software tools. The object of management is the cultivation capacity. The temperature of the Escherichia coli is accepted as a regulated technological parameter, which is controlled by changing the degree of valve opening. The method of passive experiment was used to build an automated control system. The main parameters of the control object are obtained.

Keywords: automated control system, technological process, E. coli, mathematical modeling, control object, transfer function, control parameters

The paper considers the bioreactor for cultivation of Chlorella microalgae. The indicators of the process quality and the description of the bioreactor design are given. The computation of the transfer function of the system to maintain the temperature of water in the main tank by the method of Rotach is calculated

Keywords: automation, bioreactor, biotechnology, Chlorella, system of regulation, transfer function calculation, Rotach method

The article deals with the parametric method of pump unit diagnostics. The well-known methods of diagnostics are described, the comparison of methods is given. The parametric method allows to determine the current state of the pumping unit on the basis of publicly available information in the process of liquid pumping. The article presents a mathematical model of the system frequency Converter, engine, pump. An example of changing the coefficients of the diagnostic model is given.

Keywords: centrifugal pumps, methods, diagnostics, parameters, mathematical model, coefficient, diagnostic models