In this paper we investigated the structure of the magnetic fluid based on Fe3O4 nanoparticles. Magnetic fluid based on Fe3O4 nanoparticles is used for cancer treatment, targeted drug delivery, hyperthermia, as a contrast agent in surgery, as a barrier to blood flow and others. Magnetic fluid based on Fe3O4 nanoparticles was synthesized by chemical condensation of magnetite nanoparticles. Characteristics of magnetic fluid (oxidation of iron nanoparticles size, density) were investigated using X-ray absorption spectroscopy. The changes of the antitumor effect of the magnetic fluid is associated with an increase of the particle size of the iron oxide that has a significant impact on their penetration in a tumor tissue.
Keywords: magnetic fluid, magnetite, nanoparticles, Fe3O4, oxidation state, density, antitumor activity
In this work, the nanoparticles were investigated biogenic metals iron, fine and coarse copper nanoparticles, the nanoparticles of zinc test samples showed pronounced antitumor activity in the body tumor-bearing rats. Nanoparticles were introduced into the body of rats as a solution in sodium chloride .On laboratory X-ray absorption spectrometer R-XAS Looper were measured X-ray absorption spectra (XANES) of reference samples of iron, copper, zinc foil, iron oxide, copper, zinc and investigated nanoparticles. Based on the data, it was concluded that their structure, charge state and redox pure powders and sodium chloride.
Keywords: magnetic fluid, magnetite, nanoparticles, Fe3O4, oxidation state, density, antitumor activity